Selected Literature

An inhibitory segment within G-patch activators tunes Prp43-ATPase activity during ribosome assembly.
Portugal-Calisto D, Geiger AG, Rabl J, Vadas O, Oborská-Oplová M, Mazur J, Richina F, Klingauf-Nerurkar P, Michel E, Leitner A, Boehringer D, Panse VG (2024)
Nat Commun 15: 10150

An RNA-dependent and phase-separated active subnuclear compartment safeguards repressive chromatin domains.
Lerra L, Panatta M, Bär D, Zanini I, Tan JY, Pisano A, Mungo C, Baroux C, Panse VG, Marques AC, Santoro R (2024)
Mol Cell: S1097-2765(24)00225-9

RNA recognition by Npl3p reveals U2 snRNA-binding compatible with a chaperone role during splicing.
Moursy A, Cléry A, Gerhardy S, Betz KM, Rao S, Mazur J, Campagne S, Beusch I, Duszczyk MM, Robinson MD, Panse VG, Allain FH (2023)
Nat Commun 14: 7166

The dual nature of the nucleolus.
Tartakoff A, DiMario P, Hurt E, McStay B, Panse VG, Tollervey D (2022)
Genes Dev 36: 765-769

Eukaryotic ribosome assembly and nucleocytoplasmic transport.
Oborská-Oplová M, Fischer U, Altvater M, Panse VG (2022)
Methods Mol Biol 2533: 99-126

Orchestrating ribosomal RNA folding during ribosome assembly.
Oborská-Oplová M, Gerhardy S, Panse VG (2022)
Bioessays 44: e2200066

High-throughput functional characterization of protein phosphorylation sites in yeast.
Viéitez C, Busby BP, Ochoa D, Mateus A, Memon D, Galardini M, Yildiz U, Trovato M, Jawed A, Geiger AG, Oborská-Oplová M, Potel CM, Vonesch SC, Szu Tu C, Shahraz M, Stein F, Steinmetz LM, Panse VG, Noh KM, Savitski MM, Typas A, Beltrao P (2021)
Nat Biotechnol: Online ahead of print

Puf6 primes 60S pre-ribosome nuclear export at low temperature.
Gerhardy S, Oborská-Oplová M, Gillet L, Börner R, van Nues R, Leitner A, Michel E, Petkowski JJ, Granneman S, Sigel RKO, Aebersold R, Panse VG (2021)
Nat Commun 12: 4696

The ribotoxin α-sarcin can cleave the sarcin/ricin loop on late 60S pre-ribosomes.
Olombrada M, Peña C, Rodríguez-Galán O, Klingauf-Nerurkar P, Portugal-Calisto D, Oborská-Oplová M, Altvater M, Gavilanes JG, Martínez-Del-Pozo Á, de la Cruz J, García-Ortega L, Panse VG (2020)
Nucleic Acids Res 48: 6210-6222

Divergent evolution of Legionella RCC1 repeat effectors defines the range of ran GTPase cycle targets.
Swart AL, Steiner B, Gomez-Valero L, Schütz S, Hannemann M, Janning P, Irminger M, Rothmeier E, Buchrieser C, Itzen A, Panse VG, Hilbi H (2020)
mBio 11: e00405-20

The GTPase Nog1 co-ordinates assembly, maturation and quality control of distant ribosomal functional centers.
Klingauf-Nerurkar P, Gillet LC, Portugal-Calisto D, Oplova M, Jäger M, Schubert OT, Pisano A, Peña C, Rao S, Altvater M, Chang Y, Aebersold R, Panse VG (2020)
Elife 9: e52474

Conserved phosphorylation hotspots in eukaryotic protein domain families.
Strumillo MJ, Oplová M, Viéitez C, Ochoa D, Shahraz M, Busby BP, Sopko R, Studer RA, Perrimon N, Panse VG, Beltrao P.(2019)
Nat Commun 10: 1977

Co-translational assembly of proteasome subunits in NOT1-containing assemblysomes.
Panasenko OO, Somasekharan SP, Villanyi Z, Zagatti M, Bezrukov F, Rashpa R, Cornut J, Iqbal J, Longis M, Carl SH, Peña C, Panse VG, Collart MA (2019)
Nat Struct Mol Biol 26: 110-120

Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2.
Schütz S, Michel E, Damberger FF, Oplová M, Peña C, Leitner A, Aebersold R, Allain FH, Panse VG (2018)
Nat Commun 9: 3669

Structure of a eukaryotic cytoplasmic pre-40S ribosomal subunit.
Scaiola A, Peña C, Weisser M, Böhringer D, Leibundgut M, Klingauf-Nerurkar P, Gerhardy S, Panse VG, Ban N (2018)
EMBO J 37: e98499

Ribosome levels selectively regulate translation and lineage commitment to human hematopoiesis.
Khajuria RK, Munschauer M, Ulirsch JC, Fiorini C, Ludwig LS, McFarland SK, Abdulhay NJ, Specht H, Keshishian H, Mani DR, Jovanovic M, Ellis SR, Fulco CP, Engreitz JM, Schütz S, Lian J, Gripp KW, Weinberg OK, Pinkus GS, Gehrke L, Regev A, Lander ES, Gazda HT, Lee Wy, Panse VG, Carr SA, Sankaran VG (2018)
Cell 173: 90-103

Eukaryotic ribosome assembly, transport and quality control.
Peña C, Hurt E, Panse VG (2017)
Nat Struct Mol Biol 24: 689-699

Prefabrication of a ribosomal protein subcomplex essential for eukaryotic ribosome formation.
Peña C, Schütz S, Fischer U, Chang Y, Panse VG (2016)
Elife 5: e21755

DSS1/Sem1, A Multifunctional and Intrinsically Disordered Protein.
Kragelund BB, Schenstrøm SM, Rebula CA, Panse VG, Hartmann-Petersen R (2016)
Trends Biochem Sci: 41: 446-459

Insertion of the biogenesis factor Rei1 probes the ribosome tunnel during 60S subunit maturation.
Greber BJ, Gerhardy S, Leitner A, Leibundgut M, Salem M, Boehringer D, Leulliot N, Aebersold R, Panse VG, Ban N (2016)
Cell 164: 91-102

A non-canonical mechanism for Crm1-export complex assembly.
Rothenbusch U, Schäuble N, Altvater M, Schütz S, Faza MB, Panse VG (2015)
Elife 10.7554/eLife.05745

A RanGTP-independent mechanism allows ribosomal protein nuclear import for ribosome assembly.
Schütz S, Fischer U, Altvater M, Nerurkar P, Peña C, Gerber M, Chang Y, Caesar S, Schubert OT, Schlenstedt G, Panse VG (2014)
Elife 10.7554/eLife.03473

Assembly and nuclear export of pre-ribosomal particles in budding yeast.
Gerhardy S, Menet AM, Peña C, Petkowski JJ, Panse VG (2014)
Chromosoma 123: 327-344

Non-FG mediated transport of the large pre-ribosomal subunit through the nuclear pore complex by the mRNA export factor Gle2.
Occhipinti L, Chang Y, Altvater M, Menet AM, Kemmler S, Panse VG (2013)
Nucleic Acids Res 41: 8266-8279

Targeted proteomics reveals compositional dynamics of 60S pre-ribosomes after nuclear export.
Altvater M, Chang Y, Melnik A, Occhipinti L, Schütz S, Rothenbusch U, Picotti P, Panse VG (2012)
Mol Syst Biol 8: 628

Role of Mex67-Mtr2 in the nuclear export of 40S pre-ribosomes.
Faza MB, Chang Y, Occhipinti L, Kemmler S, Panse VG (2012)
PLoS Genet 8: e1002915

Getting ready to commit: ribosomes rehearse translation.
Schütz S, Panse VG (2012)
Nat Struct Mol Biol 19: 861-862

Maturation of eukaryotic ribosomes: acquisition of functionality.
Panse VG, Johnson AW (2010)
Trends Biochem Sci 35: 260-266

Yvh1 is required for a late maturation step in the 60S biogenesis pathway.
Kemmler S, Occhipinti L, Veisu M, Panse VG (2009)
J Cell Biol 186: 863-880

Sem1 is a functional component of the nuclear pore complex-associated messenger RNA export machinery.
Faza MB, Kemmler S, Jimeno S, González-Aguilera C, Aguilera A, Hurt E, Panse VG (2009)
J Cell Biol 184: 833-846